The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice
Figure 2
Histopathological analysis of heart tissue parasitism and inflammatory infiltrate in T. cruzi-infected WT and 5-LO−/− mice (/group) on postinoculation day 16 (staining with H&E; magnification, ×200): (a) section from a WT mouse, showing numerous large amastigote nests, (b) section from a 5-LO−/− mouse, showing fewer, smaller nests, (c) section from a WT mouse, showing intense mononuclear cell infiltration, (d) section from a 5-LO−/− mouse, showing less infiltration. Photomicrographs are from one experiment representative of three independent experiments.
