The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

Figure 5

(a) Splenic CD19⁺ B-cell counts in control, infected WT and infected 5-LO^−/− mice (𝑛=10/group). Data are from one of three independent experiments. Student’s 𝑡-test (^#𝑃<0.01 versus infected WT mice). (b) T. cruzi-specific serum antibody titers in infected WT and 5-LO^−/− mice (𝑛=10/group). Data are from one of two independent experiments. ^#𝑃<0.001 versus infected WT mice.

(a)

(b)