Biomarker Analysis Revealed Distinct Profiles of Innate and Adaptive Immunity in Infants with Ocular Lesions of Congenital Toxoplasmosis
Figure 4
Biomarker signatures of innate and adaptive immunity in the peripheral blood of infants with congenital toxoplasmosis categorized as no retinochoroidal lesions (NRL), active retinochoroidal lesions (ARL), active/cicatricial retinochoroidal lesions (ACRL), and cicatricial retinochoroidal lesions (CRL) compared to noninfected controls (NI). (a) Gray-scale diagrams were assembled using the global median value of each cell subset as the cut-off mark to tag each infant as presenting “low” or “high” (innate; adaptive) levels of a given cell population. The frequency (%) of infants displaying high cell counts is provided, and the relevant data (>50%) are underscored in bold/underline format. (b) The radar charts summarize the biomarker signature of innate and adaptive immunity, where each axis displays the proportion of infants with high levels of a given cell population. The relevant data (>50%) are underscored in bold/underline format.
