Glucagon-Like Peptide-1 Secreting Cell Function as well as Production of Inflammatory Reactive Oxygen Species Is Differently Regulated by Glycated Serum and High Levels of Glucose

Figure 3

HG increases GLP-1 total production and release. Levels of total GLP-1 production (a) (calculated as the sum of the supernatant and cell content of GLP-1) and GLP-1 released (b) in the supernatants were shown. Data are expressed as mean ± SE (𝑛=5). ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 versus CTR.

(a)

(b)