A Novel Chemically Modified Curcumin Reduces Severity of Experimental Periodontal Disease in Rats: Initial Observations
Figure 2
(a) Gelatin zymography of partially purified extract of gingiva from each experimental group showing the effect of orally administered CMC 2.24 on gingival MMPs (-2, -9). In groups 1 and 3, all rats received PBS injections into the gingiva plus oral administration of either vehicle alone (group 1) or CMC 2.24 (group 3). In groups 2 and 4, all rats received LPS injections into the gingiva plus oral administration of either vehicle alone (group 2) or CMC 2.24 (group 4). (b) Densitometric analysis of gingival MMPs (-2, -9).