Involvement of Proteasome and Macrophages M2 in the Protection Afforded by Telmisartan against the Acute Myocardial Infarction in Zucker Diabetic Fatty Rats with Metabolic Syndrome
Figure 2
Effect of telmisartan on the expression of proteasome and ubiquitin. Telmisartan (tel) reduces in a dose-dependent fashion the expression of (a) 26S, (b) 20S proteasome subunits, and (c) ubiquitin in infarcted heart tissue of rats as shown by Western blot analysis. Values are reported as error. and versus control. I/R (ischemia/reperfusion); tel 7 (telmisartan 7 mg/kg); tel 12 (telmisartan 12 mg/kg).