Effects of <b><i>ω</i></b>-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome

<table>Oxidative stress markers levels (NPBI, plasma F<sub>2</sub>-IsoPs, and F<sub>4</sub>-NeuroPs) are significantly reduced in the <i>ω</i>-3 PUFAs supplemented Rett population, as compared to basal values (Panels (a)–(d)). Conversely, no significant changes were observed for 4-HNE PAs values (Panel (e)). *denotes <svg height="11.175" id="M68" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.113)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" id="x1D443"></path></g>
</svg> value &lt; 0.05. NPBI: non protein-bound iron; F<sub>2</sub>-IsoPs: plasma free F<sub>2</sub>-isoprostanes; F<sub>4</sub>-NeuroPs: plasma free F<sub>4</sub>-neuroprostanes; 4-HNE protein adducts: 4-hydroxynonenal protein adducts; mo.s: months.</table>

Mediators of Inflammation

fig2

Figure 2

Figure 2: Effects of <b><i>ω</i></b>-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome 

Mediators of Inflammation

Effects of ω-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome

Figure 2