Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase

Table 2

Quantification of RGC survival in wild type, MMP-2 null (MMP-2^−/−), and MMP-9 null (MMP-9^−/−) mice, after ONC (4 dpi). RGC densities (RGCs/mm²) per retina are depicted. , number of animals.

	Naive			ONC
	Wild type	MMP-2^−/−	MMP-9^−/−	Wild type	MMP-2^−/−	MMP-9^−/−
	3393	3059	3551	2317	2327	2342
	3265	2928	3458	2473	2262	2663
	3660	3580	3481	2785	2606	2939
	3309	3810	3932	1952	2154	2695
	3187	3759	1825	2856	2641	3122
	3464	2938	2240	2463	2149	2880
			2192		2230	2663
						3209
Mean	3380	3346	2954	2475	2338	2813
SEM	68	169	316	134	77	99
	6	6	7	6	7	8