Table 2: Comparison of miRNA expression profiles between sarcoidosis (S) patients, subdivided according to the outcome after 2-year follow-up (Reg: regression; Prog: progression), and control subjects (C). All the data are presented as Mean Expression Level (95% confidence interval). Results are expressed relative to levels of endogenous U6 miRNA. : number of patients. Bold font indicates significant value.
 SReg SProg SC
( = 48)( = 28)( = 20)( = 14)(Kruskal-Wallis)S versus CReg versus Prog
miR-let-7c-5p0.058
(0.051–0.066)		0.051
(0.042–0.060)		0.069
(0.056–0.082)		0.069
(0.052–0.087)		0.1270.2390.039
miR-let-7d-5p0.136
(0.118–0.154)		0.124
(0.100–0.147)		0.153
(0.126–0.181)		0.155
(0.120–0.190)		0.2500.2560.103
miR-21-5p2.022
(1.618–2.427)		1.676
(1.300–2.051)		2.508
(1.693–3.323)		2.023
(1.253–2.794)		0.5850.8330.161
miR-24-3p0.522
(0.462–0.582)		0.488
(0.409–0.567)		0.570
(0.473–0.667)		0.571
(0.432–0.711)		0.4320.4050.174
miR-25-3p0.110
(0.071–0.150)		0.117
(0.050–0.184)		0.101
(0.077–0.124)		0.089
(0.042–0.137)		0.4850.4340.191
miR-92a-3p0.364
(0.312–0.416)		0.319
(0.255–0.384)		0.421
(0.336–0.506)		0.362
(0.272–0.452)		0.2770.8140.061
miR-125a-5p0.044
(0.034–0.054)		0.046
(0.029–0.062)		0.042
(0.031–0.052)		0.058
(0.020–0.096)		0.9820.8140.770
miR-126-3p0.054
(0.005–0.102)		0.077
(0.007–0.160)		0.021
(0.012–0.030)		0.057
(0.004–0.118)		0.9920.8600.810
miR-133a-3p0.012
(0.010–0.015)		0.012
(0.008–0.015)		0.013
(0.009–0.017)		0.014
(0.010–0.018)		0.5890.2480.557
miR-146a-5p0.304
(0.266–0.342)		0.294
(0.235–0.352)		0.319
(0.271–0.366)		0.196
(0.135–0.257)		0.0200.0060.331
miR-148a-3p0.061
(0.050–0.072)		0.056
(0.042–0.069)		0.068
(0.049–0.087)		0.074
(0.050–0.097)		0.5070.3420.268
miR-150-5p0.280
(0.219–0.340)		0.277
(0.199–0.355)		0.283
(0.179–0.386)		0.093
(0.061–0.125)		<0.001<0.0010.983
miR-155-5p0.200
(0.170–0.231)		0.169
(0.138–0.200)		0.244
(0.187–0.300)		0.168
(0.126–0.210)		0.1110.5500.017
miR-181a-5p0.106
(0.091–0.121)		0.102
(0.084–0.120)		0.112
(0.085–0.139)		0.122
(0.091–0.153)		0.6500.2630.630
miR-199a-5p0.012
(0.010–0.014)		0.011
(0.008–0.014)		0.013
(0.009–0.016)		0.016
(0.007–0.024)		0.9190.7480.532
miR-202-3p0.009
(0.008–0.011)		0.010
(0.007–0.013)		0.013
(0.006–0.020)		0.014
(0.009–0.019)		0.1730.0360.564
miR-204-5p0.008
(0.006–0.010)		0.006
(0.005–0.007)		0.010
(0.005–0.015)		0.011
(0.007–0.015)		0.0300.0310.061
miR-2060.026
(0.002–0.064)		0.039
(0.003–0.101)		0.010
(0.001–0.021)		0.005
(0.003–0.007)		0.9990.9280.963
miR-212-3p0.010
(0.008–0.013)		0.010
(0.008–0.012)		0.011
(0.006–0.017)		0.012
(0.009–0.016)		0.4900.1580.705
miR-214-3p0.009
(0.006–0.011)		0.008
(0.006–0.010)		0.010
(0.005–0.014)		0.010
(0.005–0.014)		0.9680.8660.621
miR-222-3p0.038
(0.029–0.048)		0.059
(0.047–0.072)		0.065
(0.050–0.080)		0.062
(0.052–0.071)		0.0590.0120.668
miR-223-3p0.808
(0.679–0.936)		0.815
(0.615–1.014)		0.798
(0.644–0.951)		0.901
(0.695–1.106)		0.6920.2700.826
miR-302c-3p0.061
(0.048–0.074)		0.060
(0.041–0.079)		0.065
(0.046–0.083)		0.089
(0.034–0.143)		0.8200.4270.631
miR-424-5p0.103
(0.002–0.289)		0.013
(0.002–0.025)		0.009
(0.006–0.012)		0.018
(0.005–0.031)		0.4260.1430.905
miR-503-5p0.038
(0.030–0.046)		0.041
(0.030–0.052)		0.035
(0.023–0.046)		0.058
(0.022–0.094)		0.4800.6430.112