Research Article

Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages

Figure 1

Intravitreal Resolvin D1 (RvD1) improves the clinical score in rats with EIU. The rats were treated with vehicle (saline+ethanol), LPS (200 μg/rat), and LPS+RvD1 at the dose of 10-100-1000 ng/kg 1 h post-LPS treatment and were evaluated 24 h after injections. Clinical manifestations of EIU were graded as reported in test (see Section 2). Values are reported as the mean ± SEM, of observation for each experimental group. and compared with LPS-treated group.