Research Article
Lack of Association between Polymorphisms of the TLR4 Gene and Infection with the Hepatitis B and C Viruses
Table 2
Genotype, allele, and haplotype frequencies of SNPs of the TLR4 gene in the investigated groups.
| | SNPs | HBV
(%) | HCV
(%) | Control
(%) | p1 | p2 |
| | rs4986790 (A>G) | | | | | | | AA | 48 (97.96) | 67 (93.06) | 276 (92.31) | 0.2445 | 0.7990 | | AG | 1 (2.04) | 5 (6.94) | 22 (7.36) | | GG | 0 | 0 | 1 (0.33) | | A | 97 (98.98) | 139 (96.52) | 574 (95.99) | 0.1903 | 0.9510 | | G | 1 (1.02) | 5 (3.47) | 24 (4.01) | | rs4986791 (C>T) | | | | | | | CC | 40 (97.56) | 68 (94.44) | 276 (92.31) | 0.3641 | 0.6891 | | CT | 1 (2.44) | 4 (5.56) | 22 (7.36) | | TT | 0 | 0 | 1 (0.33) | | C | 81 (98.78) | 140 (97.22) | 574 (95.99) | 0.3009 | 0.6417 | | T | 1 (1.22) | 4 (2.78) | 24 (4.01) | | Haplotypes | | | | | | | AA/CC | 39 (95.12) | 67 (93.05) | 271 (90.64) | 0.6409 | 0.9305 | | AA/CT | 1 (2.44) | 0 | 5 (1.67) | | AA/TT | 0 | 0 | 0 | | AG/CC | 1 (2.44) | 1 (1.39) | 4 (1.34) | | AG/CT | 0 | 4 (5.56) | 17 (5.69) | | AG/TT | 0 | 0 | 1 (0.33) | | GG/CC | 0 | 0 | 1 (0.33) | | GG/CT | 0 | 0 | 0 | | GG/TT | 0 | 0 | 0 |
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p1: HBV versus control; p2: HCV versus control.
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