Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives

Table 2

Overview of the medical literature regarding anti-interleukin-1 therapies in the monogenic autoinflammatory disorders.

	FMF	TRAPS	MKD	CAPS	PAPAs	MAJEEDs	BS
Anakinra	[44–58]	[59]; [60–64]	[65–72]	[73]; [74–94]	[95–100]	[38]	[101, 102]
Canakinumab	[46, 50]; [58, 103, 104]	[105–107]	[68]	[93, 94, 108–116]	[117]	[38]	[118]
Rilonacept	[50]; [119–121]			[122–128]

BS: Blau syndrome; CAPS: cryopyrin-associated periodic syndromes; FMF: familial Mediterranean fever; MAJEEDs: Majeed syndrome; MKD: mevalonate kinase deficiency syndrome; PAPAs: pyogenic arthritis-pyoderma gangrenosum-acne syndrome; TRAPS: tumor necrosis factor receptor-associated periodic syndrome.