ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF-α and NF-κB P65

Table 1

Mankin histological grading system.

Category	Grade
(1) Structure
(a) Normal	0
(b) Surface irregularity	1
(c) Pannus and surface irregularity	2
(d) Clefts to transitional zone	3
(e) Clefts to radial zone	4
(f) Clefts to calcified zone	5
(g) Complete disorganization	6
(2) Cells
(a) Normal	0
(b) Diffuse hypercellularity	1
(c) Cloning	2
(d) Hypocellularity	3
(3) Safranin-O staining
(a) Normal	0
(b) Slight reduction	1
(c) Modest reduction	2
(d) Severe reduction	3
(e) No dye noted	4
(4) Tidemark integrity
(a) Intact	0
(b) Crossed by blood vessels	1