Role of Polymorphisms of Inducible Nitric Oxide Synthase and Endothelial Nitric Oxide Synthase in Idiopathic Environmental Intolerances

Table 2

Allelic distributions of the NOS2A promoter pentanucleotide microsatellite −2.5 kb (CCTTT)_n in IEI patients and healthy subjects.

Genotype NOS2A; −2.5 kb (CCTTT	MCS; ()	SMCS; ()	FM/CFS; ()	Controls; ()
8	0.03^a	0.02^b	0^c	0.09
9	0.07	0.09	0.04	0.08
10	0.17	0.19	0.18	0.18
11	0.15	0.16	0.26^d	0.09
12	0.28	0.27	0.32	0.27
13	0.15	0.08	0.10	0.12
14	0.07	0.05	0.04	0.06
15	0.07	0.08	0.04	0.07
16	0.01^e,f	0.08	0.02	0.04

MCS, multiple chemical sensitivity; SMCS: suspected multiple chemical sensitivity; FM/CFS, fibromyalgia/chronic fatigue syndrome; controls, healthy subjects. a: , significant difference in comparison with controls; b: 0.0482, significant difference versus controls; c: , significant difference versus controls; d: , significant difference versus controls; e: , significant difference versus controls; f: , significant difference versus SMCS.