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Mediators of Inflammation
Volume 2015, Article ID 274607, 11 pages
Research Article

Reduced Serum Butyrylcholinesterase Activity Indicates Severe Systemic Inflammation in Critically Ill Patients

Department of Anesthesiology, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany

Received 3 September 2014; Revised 27 December 2014; Accepted 3 January 2015

Academic Editor: Stefanie B. Flohé

Copyright © 2015 Aleksandar R. Zivkovic et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary figure 1. Interaction between BChE activity and disease severity scores during the course of the systemic inflammation. Diagrams illustrate the dynamic changes of the BChE activity (red line) and the disease severity scores (APACHE II: black line; SOFA: black dotted line; SAPS II: black dashed line) over the time course of 2-6 days. Note that only patients who were consecutively monitored for both BChE activity and for the disease severity scores for more than 2 days were included (n = 20 patients). BChE: butyrylcholinesterase; SAPS: simplified acute physiology score; SOFA: sequential organ failure assessment; APACHE: acute physiology and chronic health evaluation.

  1. Supplementary Material