Elevated Serum Levels of Soluble TNF Receptors and Adhesion Molecules Are Associated with Diabetic Retinopathy in Patients with Type-1 Diabetes

Figure 2

Three clusters of functionally related proteins with strong positive correlations. The pairwise correlations between all eight proteins were examined in T1D patients with and without DR separately. Correlation between individual protein levels was computed using Pearson correlation coefficient. Clustering and visualization of correlation matrix was performed using hierarchical clustering method and heatmap. Three clusters of functionally related proteins were found with strong positive correlations.