N-Acetyl-seryl-aspartyl-lysyl-proline Alleviates Renal Fibrosis Induced by Unilateral Ureteric Obstruction in BALB/C Mice

Figure 2

Histological changes. (a–d) PAS staining at day 7 of control animals (a), UUO operated animals (b), UUO animals with Ac-SDKP treatment (c), and UUO animals with Captopril treatment (d). Magnification (400x). (e) Tubulointerstitial injury index of renal cortex for assessing tubular and interstitial damage and graded in an observer-blinded manner from an arbitrary scale of 0–5 (1 ≤ 10%; 2 = 10–25%; 3 = 26–50%; 4 = 51–75%; 5 = 76–95%; 6 ≥ 95%).

(a)

(b)

(c)

(d)

(e)