Activins and Follistatin in Chronic Hepatitis C and Its Treatment with Pegylated-Interferon-α Based Therapy

Figure 3

The production of activin-A and follistatin by normal and abnormal hepatocyte. Activin-A and follistatin regulate hepatocyte regeneration in healthy liver. Pathological increase of both activin-A and follistatin by the hepatocyte is associated with several liver diseases including fibrosis, cirrhosis, and hepatocellular carcinoma.