Anti-Inflammatory Properties of Low and High Doxycycline Doses: An In Vitro Study

Figure 2

Evaluation of cell viability in HaCaT cells stimulated with LPS (25 μg/mL) and incubated in pretreatment, concomitant, and posttreatment settings with low (0.3 mg/μL; 0.6 mg/μL) and high (1.5 mg/μL; 3 mg/μL) doxycycline doses. (a, c) Cell viability was measured at 48 h in pre- and posttreatment and (b) at 24 h in concomitant treatment. Statistical significance was determined with respect to the viability of nonstimulated cells (, ).

(a)

(b)

(c)