Disturbances of Modulating Molecules (FOXP3, CTLA-4/CD28/B7, and CD40/CD40L) mRNA Expressions in the Orbital Tissue from Patients with Severe Graves’ Ophthalmopathy

Table 1

Characteristics of patients.

	Severe course of GO	Mild course of GO	Mild + severe GO
Number of patients	20	6	26
Age	42.3 (36–46)	46.2 (42–49)	44.5 years (36–49)
Gender	19F; 1M	6F	25F; 1M
Smokers	88%	50%	77%
TRAb (mean ± SD)
CAS	7.1 (4–10)	2 (1–3)	5.92 (1–10)
NOSPECS	8.55 (5–13)	3.83 (2–5)	7.46 (2–13)
Proptosis right	18 (14.5–25)	16.25 (14–18)	17.5 (14–25)
Proptosis left	19.5 (15–25)	16.5 (14–21.5)	17.5 (14–25)