Relationship among Short and Long Term of Hypoinsulinemia-Hyperglycemia, Dermatophytosis, and Immunobiology of Mononuclear Phagocytes

Figure 1

Experimental design. Mice were intravenously inoculated with alloxan (60 mg kg⁻¹) into the caudal vein. Hyperglycemia was confirmed after 48 h by blood glucose levels >200 mg dL⁻¹. (a) Mice that were exposed to HH condition for 7 days constituted the HH group (short term) and those for 21 days constituted the HH group (long term). Mice from HH groups (short and long term) were infected with 2 × 10⁷ T. mentagrophytes microconidia into footpad. (b) Glucose levels (mg dL⁻¹) after 7 days (short term) and 21 days (long term) of HH installation. The results are expressed as mean ± SD (/group). Unpaired -test, . and indicate statistical differences among HH group versus the control group (uninfected/HH-free mice).

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