Comprehensive Screening of Gene Function and Networks by DNA Microarray Analysis in Japanese Patients with Idiopathic Portal Hypertension

Figure 3

IPA network illustration of the relationships among gene groups showing significantly increased/decreased expression in the presence of IPH. Genes colored pink or red exhibited increased expression, while genes colored green exhibited reduced expression. The straight lines indicate direct relationships among genes, while broken lines indicate indirect relationships. (a) Illustration of the first selected pathway combined with the second pathway. (b) Illustration of the first pathway combined with the third and fifth pathways. Similar to the results from Ingenuity iReport analysis, reduced expression of ENTPD4, ABCC1, ADA, and TGF-β and increased expression of CYP4F3 were observed inside the IPA network.

(a)

(b)