Glycyrrhizic Acid Promotes M1 Macrophage Polarization in Murine Bone Marrow-Derived Macrophages Associated with the Activation of JNK and NF-κB

Figure 6

Effect of GA on BMDMs phagocytosis and bactericidal activity. BMDMs were pretreated with GA (100 μg/mL) for 12 h. (a) Incubated with FITC-dextran at 37°C for 1 h, the intracellular FITC-dextran was measured by FACS. (b) After being infected with E. coli K88 or S. typhimurium for 1 h, washed, and incubated in DMEM with gentamicin (25 μg/mL) for 0 h or 24 h, these cells were lysed, diluted, and plated on LB plates for colony enumeration. Data are mean ± SD for three independent experiments. (-test).

(a)

(b)