A Single Nucleotide Polymorphism (rs4236480) in TRPV5 Calcium Channel Gene Is Associated with Stone Multiplicity in Calcium Nephrolithiasis Patients
Table 4
Association analysis of TRPV5 rs4236480 and clinical biochemical data.
SNP
Genotype
Urine creatinine (UCr; mg/dL)
Urine calcium (UCa; mg/dL)
UCa/UCr
Urine uric acid (UUA; mg/dL)
UUA/UCr
Serum creatinine (mg/dL)
Serum calcium (mg/dL)
Serum uric acid (mg/dL)
ā
TT
93.44 76.47
5.53 2.93
0.10 0.10
42.45 28.59
0.52 0.11
1.36 0.87
8.77 0.21
5.72 1.30
rs4236480
CT
85.85 50.35
10.77 8.42
0.14 0.11
44.35 26.63
0.54 0.16
1.14 0.73
8.96 0.47
6.66 1.93
ā
CC
97.36 64.87
10.74 7.39
0.15 0.10
43.45 25.22
0.50 0.16
1.20 0.99
8.87 0.73
6.47 1.67
value
0.3983
0.2521
0.5720
0.9555
0.1162
0.4514
0.5055
0.4945
: number of patients for the statistical analysis. The value (genotype model) corresponding to the likelihood ratio test was obtained from a comparison with the null model and was adjusted for sex and age.