Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction
Free DNA in murine CF lung disease in vivo. (a) CXCR2 chemokines in BALF from βENaC-transgenic (βENaC-Tg, ) and wild-type (WT, ) mice. Levels of CXCL1 (KC) and CXCL2 (MIP-2) were quantified by ELISA. (b) Free DNA in BALs from βENaC-Tg mice. Free DNA was quantified in BALF from βENaC-Tg (filled circles, ) and wild-type (empty circles, ) mice. (c) Correlation of free DNA with CXCL2 levels in BAL. (d) Correlation of free DNA with lung function (FEV100). .
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