Pegylated Interferon- Modulates Liver Concentrations of Activin-A and Its Related Proteins in Normal Wistar Rat

Table 2

Mean ± SD of body weight, total liver weight, liver enzymes, albumin, renal function, and metabolic parameters in the different study groups.

	Control	Peg-INF only	Peg-INF & ribavirin	Ribavirin only
Body weight (g)	221.57 ± 20.01	231.97 ± 23.01	218.42 ± 13.64	230.1 ± 22.2
Liver weight (g)	11.04 ± 1.26	10.54 ± 1.52	10.27 ± 0.44	10.23 ± 1.5
ALT (U/L)	60.4 ± 16.2	68.8 ± 18.6	53.9 ± 19	64.1 ± 11.5
AST (U/L)	92.4 ± 24.2	129.8 ± 46.7	119 ± 21.6	133 ± 49.8
Albumin (g/dL)	3.4 ± 0.4	3.3 ± 0.5	3.7 ± 0.3	3.5 ± 0.5
Creatinine (mg/dL)	0.22 ± 0.03	0.2 ± 0.06	0.2 ± 0.03	0.19 ± 0.03
Urea (mg/dL)	47.6 ± 5.1	52.3 ± 4	56.6 ± 9.5	47.3 ± 5.8
BUN (mg/dL)	22.2 ± 2.4	24.4 ± 1.9	26.3 ± 4.4	22 ± 2.7
Glucose (mg/dL)	110.7 ± 12.7	118.9 ± 23.1	112.6 ± 12.7	114.5 ± 16.1
Triglycerides (mg/dL)	77.3 ± 20.3	68.3 ± 13.9	63.2 ± 9.5	85 ± 28.5
Cholesterol (mg/dL)	45 ± 7.2	58.5 ± 12.4	62.2 ± 14.5	64.8 ± 9.7
HDL-C (g/dL)	36.2 ± 9.2	44.3 ± 1.2	52.8 ± 7.8	53.1 ± 7.7
LDL-C (g/dL)	6.6 ± 1.7	8.14 ± 2.33	7.1 ± 2.5	6.3 ± 1.55