Monocytic Tissue Transglutaminase in a Rat Model for Reversible Acute Rejection and Chronic Renal Allograft Injury

Figure 8

Vascular remodeling in renal allografts 12 weeks after transplantation from recipients treated with transglutaminase inhibitor cystamine or placebo. The relative arterial thickness (a) and the frequency of intimal hyperplasia (b) were investigated on histological sections from placebo- (c) or cystamine-treated (d) animals stained with orcein. Box plots indicate median and percentiles 0, 25, 75, and 100.

(a)

(b)

(c)

(d)