Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut
Predicted structural domains within mouse Gimap5. (a) Mouse Gimap5 is a 308-amino acid protein that contains an AIG1 domain (residues 24–227), a P-loop NTPase domain (residues 1–168), two coiled-coil domains (residues 187–221 and 239–265), and a transmembrane domain (residues 284–304). The GC missense mutation in sphinx mice at residue 38 is indicated. (b) Schematic overview of the domain features present in the different Gimap family members.
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