Research Article

Gene Expression Profiling of IL-17A-Treated Synovial Fibroblasts from the Human Temporomandibular Joint

Figure 3

Network of the IL-17A pathway by Ingenuity Pathway Analysis (IPA). Data were analyzed using the Ingenuity Pathway Analysis system (Ingenuity System, http://www.ingenuity.com/). (a) IL-17A-induced genes associated with rheumatoid arthritis. (b) Network 1 of IL-17A-induced genes by IPA. The intensity of the node color indicates the degree of upregulation (red). Nodes are indicated by various shapes that represent the functional class of the gene product. The lines are displayed with various labels that describe the nature of the relationship between the nodes.
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