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Mediators of Inflammation
Volume 2015, Article ID 453020, 13 pages
Research Article

Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms

1Institute for Medical Research, University of Belgrade, 11129 Belgrade, Serbia
2Clinic of Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center of Serbia, 11000 Belgrade, Serbia
3Clinic of Hematology, Clinical Center of Serbia, 11000 Belgrade, Serbia
4Medical Faculty, University of Belgrade, 11000 Belgrade, Serbia
5Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA

Received 26 June 2015; Revised 2 September 2015; Accepted 9 September 2015

Academic Editor: Hannes Neuwirt

Copyright © 2015 Vladan P. Čokić et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The statistical analyses of total gene expression in MPNs according to JAK2V617F mutant allele burden. We observed 261 significantly changed genes in PV, 82 significantly changed genes in ET, and 94 genes in PMF comparing to healthy subjects.

  1. Supplementary Material