Research Article

MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction

Figure 3

Heat map visualization and pathway analysis of differentially expressed genes. (a) Hierarchical clustering and heat map visualization of the differentially expressed genes after agomir based upregulation of miR-208a. (b) Apoptosis pathway analysis highlighted Bax, Caspase8, and RAS as the miR-208a regulated genes involved in the canonical apoptosis pathways.
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