Research Article
HLA Haplotypes and Genotypes Frequencies in Brazilian Chronic Periodontitis Patients
Table 4
HLA haplotype associations between chronic periodontitis patients and controls
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| HLA haplotypes | Patients (%) | Controls (%) | P | | OR (95% CI) |
| A 02/B 40 | 9 (4.2) | 0 (0.0) | <0.001 | 0.03 | undf (2.83–undf) | A03/B51 | 5 (2.5) | 0 (0.0) | 0.012 | 0.36 | undf (1.29–undf) | A26/B38 | 5 (2.3) | 0 (0.0) | 0.012 | 0.36 | undf (1.29–undf) | B40/C03 | 12 (5.6) | 5 (1.7) | 0.022 | 0.62 | 3.49 (1.12–12.83) | B18/C12 | 4 (1.9) | 0 (0.0) | 0.03 | 0.93 | undf (0.93–undf) | B51/C01 | 4 (1.9) | 0 (0.0) | 0.30 | 0.93 | undf (0.93–undf) | B 15/DRB1 11 | 0 (0.0) | 13 (4.3) | 0.001 | 0.04 | undf (0–0.45) | B40/DRB107 | 6 (2.8) | 0 (0.0) | 0.005 | 0.19 | undf (1.67–undf) | B50/DRB104 | 4 (1.9) | 0 (0.0) | 0.030 | 1.14 | undf (0.93–undf) | DQA101:02/DQB106:09 | 5 (2.3) | 0 (0.0) | 0.012 | 0.23 | undf (1.30–undf) | DRB113/DQA101:02/DQB106:09 | 5 (2.3) | 0 (0.0) | 0.012 | 0.25 | undf (1.29–undf) |
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undf = undefined. Total group (smokers, nonsmokers, and ex-smoking patients and controls). Bold font: significant after Bonferroni correction.
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