Research Article

HLA Haplotypes and Genotypes Frequencies in Brazilian Chronic Periodontitis Patients

Table 4

HLA haplotype associations between chronic periodontitis patients and controls.

HLA haplotypesPatients 

(%)
Controls 

(%)
P OR (95% CI)

A 02/B 409 (4.2)0 (0.0)<0.0010.03undf (2.83–undf)
A03/B515 (2.5)0 (0.0)0.0120.36undf (1.29–undf)
A26/B385 (2.3)0 (0.0)0.0120.36undf (1.29–undf)
B40/C0312 (5.6)5 (1.7)0.0220.623.49 (1.12–12.83)
B18/C124 (1.9)0 (0.0)0.030.93undf (0.93–undf)
B51/C014 (1.9)0 (0.0)0.300.93undf (0.93–undf)
B 15/DRB1 110 (0.0)13 (4.3)0.0010.04undf (0–0.45)
B40/DRB1076 (2.8)0 (0.0)0.005 0.19undf (1.67–undf)
B50/DRB1044 (1.9)0 (0.0)0.0301.14undf (0.93–undf)
DQA101:02/DQB106:095 (2.3)0 (0.0)0.0120.23undf (1.30–undf)
DRB113/DQA101:02/DQB106:095 (2.3)0 (0.0)0.0120.25undf (1.29–undf)

undf = undefined.
Total group (smokers, nonsmokers, and ex-smoking patients and controls).
Bold font: significant after Bonferroni correction.