Mediators of Inflammation / 2015 / Article / Tab 3

Research Article

Effect of Helicobacter pylori Eradication on TLR2 and TLR4 Expression in Patients with Gastric Lesions

Table 3

Comparisons of TLR2 and TLR4 mRNA expression levels according to cagA and vacA genotypes of H. pylori in infected patients before and after bacteria eradication treatment.

TLR2 TLR4
Samples (%)RQ median (range) valueSamples (%)RQ median (range) value

Before treatment
cagA+ 11/23 (48.0)1.3211/23 (48.0)1.750.689
0.66–23.050.5180.65–11.09
cagA− 12/23 (52.0)1.4112/23 (52.0)1.80
0.71–12.630.97–7.17
vacA s1m1 12/25 (48.0)1.5112/25 (48.0)1.970.978
0.67–12.630.8490.65–7.17
vacA others 13/25 (52.0)1.3113/25 (52.0)2.02
0.66–23.050.97–11.09
After treatment
 Eradicated
  cagA+5/11 (46.0)1.555/12 (42.0)1.610.876
0.50–7.210.6621.06–12.01
  cagA− 6/11 (54.0)2.167/12 (58.0)2.69
0.59–43.120.64–28.07
  vacA s1m1 7/13 (54.0)0.717/13 (54.0)1.420.234
0.34–7.210.2340.64–12.01
  vacA others6/13 (46.0)2.656/13 (46.0)3.30
0.59–43.120.89–28.07
 Noneradicated
  cagA+ 6/12 (50.0)1.876/10 (60.0)1.990.762
1.03–5.610.6990.56–3.92
  cagA− 6/12 (50.0)1.344/10 (40.0)2.59
0.37–6.360.82–9.75
  vacA s1m1 5/12 (42.0)1.364/11 (36.4)1.660.230
0.65–5.610.6390.56–2.99
  vacA others 7/12 (58.0)1.927/11 (63.6)3.52
0.37–6.360.82–9.75

vacAothers (s1m2, s2m2, s1_, s2_, and _m1); value = Mann-Whitney test; .

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