The In Vivo Granulopoietic Response to Dexamethasone Injection Is Abolished in Perforin-Deficient Mutant Mice and Corrected by Lymphocyte Transfer from Nonsensitized Wild-Type Donors

Figure 2

Total leukocyte, lymphocyte, and granulocyte counts in peripheral blood of Pfp mice and B6 wild-type controls. Data are Mean + SEM of total leukocyte (a), lymphocyte (b), neutrophil (c), and eosinophil (d) in 1 mL of peripheral blood of B6 (white bars) and Pfp (black bars) matched by weight (median = 21 g, range 19 g–23 g; for both). Significant difference between the indicated groups.

(a)

(b)

(c)

(d)