TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2

Figure 3

TGF-β blockade upregulates CCN2(IV)-induced renal chemokine expression. Kidney gene expression of MCP-1 and RANTES was evaluated by real time PCR. Data are expressed as -fold increase over control as mean ± SEM of 10 animals per group. versus control. versus CCN2(IV)-IgG.