Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women

Figure 5

BDNF inhibits CRP-induced DNA damage. HMVEC-Cs untreated or treated with 25 μM menadione (Men), 25 μg/mL CRP (CRP), 10 ng/mL BDNF (BDNF), or BDNF and CRP (BDNF + CRP) and then fixed and stained with anti-8-oxoG antibodies. Fluorescent intensity for 8-oxoG stained nuclei was quantified and the histogram represents the normalized mean + SEM from 4 experiments. using one-way ANOVA and Tukey’s post hoc test.