Expression of Chemokine Receptors on Peripheral Blood T Cells in Children with Chronic Kidney Disease
Table 4
Absolute values of T cell subpopulations, including populations with expression of receptors for selected chemokines in examined children and healthy controls.
Lymphocyte subpopulations G/l]
HD group
CKD group
Control group
T lymphocytes
1.4 ± 0.5
1.5 ± 0.9
1.8 ± 0.6
0,0577
CD4+ T cells
0.78 ± 0,4
0.85 ± 0.6
0.94 ± 0.4
0,1629
CD8+ T cells
0.58 ± 0.3
0.65 ± 0.3
0.62 ± 0.3
0,7768
CCR7+ T cells
0.31 (0.04–0.8)
0.41 (0.1–0.7)
0.06 (0.005–1.8)
0,3883
CD45RO+CCR7+
0.04 (0.011–0.1)
0.06 (0.01–0.35)
0.02 (0.01–0.58)
0,8162
CD28+CCR7+ T cells
0.31 (0.04–0.8)
0.38 (0.1–0.7)
0.06 (0.01–1.8)
0,7937
CXCR4+ T cells
0,27 ± 0,21
0,49 ± 0,32
0,55 ± 0,46
0,0387
CXCR4+CD4+ T cells
0,04 (0,00003–0,4)
0,013 (0,02–0,4)
0,2 (0,00001–0,9)
0,0621
CXCR4+CD8+ T cells
0,1 (0,03–0,6)
0,3 (0,04–0,9)
0,2 (0,02–1,1)
0,3762
CXCR4+CCR5+ T cells
0,01 (0,00002–0,2)
0,1 (0,02–0,4)
0,1 (0,00001–0,2)
0,0639
CCR5+ T cells
0,32 ± 0,22
0,29 ± 14
0,41 ± 0,32
0,2499
CCR5+CD4+ T cells
0,07 ± 0,04
0,07 ± 0,03
0,1 ± 0,07
0,0636
CCR5+CD8+ T cells
0,1 (0,02–0,6)
0,2 (0,05–0,4)
0,1 (0,02–0,6)
0,4947
CCR4+ T cells
0,16 ± 0,13
0,16 ± 0,15
0,27 ± 0,26
0,1433
CCR4+CD4+ T cells
0,1 (0,02–1,2)
0,1 (0,03–0,2)
0,1 (0–0,4)
0,3578
CCR4+CD8+ T cells
0,05 (0,00004–0,3)
0,02 (0,00002–0,8)
0,03 (0,00001–0,9)
0,9535
CXCR3+ T cells
0,63 ± 0,31
0,63 ± 0,26
0,84 ± 0,33
0,0294
CXCR3+CD4+ T cells
0,2 ± 0,09
0,2 ± 0,07
0,25 ± 0,12
0,1813
CXCR3+CD8+ T cells
0,35 ± 0,22
0,35 ± 0,15
0,46 ± 0,21
0,0789
CXCR3+CCR5+ T cells
0,25 ± 0,17
0,23 ± 0,12
0,30 ± 0,23
0,5108
CXCR3+CXCR4+ T cells
0,17 ± 0,14
0,26 ± 0,18
0,25 ± 0,23
0,4623
Absolute values are shown as mean ± standard deviation for Gaussian distribution, otherwise as median (minimum–maximum). : significance in ANOVA test.
