Research Article

Excessive Daytime Sleepiness Is Associated with Changes in Salivary Inflammatory Genes Transcripts

Table 5

Comparison of transcriptional changes in high and low BMI subjects.

GeneAbbreviationBMI < 30BMI > 30-test
fold  fold  

-actinACTB1.39 ± 0.291.65 ± 0.400.438
Arachidonate 5-lipoxygenaseALOX51.46 ± 0.330.97 ± 0.280.117
Arachidonate 12-lipoxygenaseALOX121.25 ± 0.470.48 ± 0.320.058
Annexin A1ANXA13.06 ± 1.252.33 ± 1.030.529
Annexin A3ANXA31.68 ± 0.401.63 ± 0.610.913
Annexin A5ANXA51.74 ± 0.582.17 ± 0.750.519
-2-microglobulinB2M1.95 ± 0.663.12 ± 0.910.156
Caspase 1, apoptosis-related cysteine peptidaseCASP12.68 ± 0.903.05 ± 1.420.741
Glyceraldehyde-3-phosphate dehydrogenaseGAPDH2.14 ± 0.721.94 ± 0.570.771
Intercellular adhesion molecule 1ICAM10.61 ± 0.220.62 ± 0.360.982
Interleukin 1 receptor, type IIIL1R21.88 ± 0.531.24 ± 0.340.153
Interleukin 2 receptor, gammaIL2RG2.65 ± 1.372.20 ± 0.930.713
Integrin, alpha MITGAM1.56 ± 0.481.25 ± 0.510.537
Integrin, beta 2ITGB21.52 ± 0.351.54 ± 0.380.949
Mitogen-activated protein kinase 1MAPK11.77 ± 0.831.20 ± 0.370.355
Mitogen-activated protein kinase 3MAPK31.41 ± 0.360.90 ± 0.340.156
Mitogen-activated protein kinase 14MAPK142.18 ± 0.601.51 ± 0.450.211
Phosphodiesterase 4B, cAMP-specificPDE4B1.44 ± 0.361.44 ± 0.550.999
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)PTGS22.43 ± 0.843.42 ± 1.130.338
Tumor necrosis factor receptor superfamily, member 1ATNFRSF1A1.47 ± 0.361.40 ± 0.330.841
Tumor necrosis factor receptor superfamily, member 1BTNFRSF1B1.72 ± 0.660.86 ± 0.360.099

Mean ± SEM.
= 15–24.
= 11–15.