Research Article
Excessive Daytime Sleepiness Is Associated with Changes in Salivary Inflammatory Genes Transcripts
Table 5
Comparison of transcriptional changes in high and low BMI subjects.
| Gene | Abbreviation | BMI < 30 | BMI > 30 | -test |
fold | fold |
| -actin | ACTB | 1.39 ± 0.29 | 1.65 ± 0.40 | 0.438 | Arachidonate 5-lipoxygenase | ALOX5 | 1.46 ± 0.33 | 0.97 ± 0.28 | 0.117 | Arachidonate 12-lipoxygenase | ALOX12 | 1.25 ± 0.47 | 0.48 ± 0.32 | 0.058 | Annexin A1 | ANXA1 | 3.06 ± 1.25 | 2.33 ± 1.03 | 0.529 | Annexin A3 | ANXA3 | 1.68 ± 0.40 | 1.63 ± 0.61 | 0.913 | Annexin A5 | ANXA5 | 1.74 ± 0.58 | 2.17 ± 0.75 | 0.519 | -2-microglobulin | B2M | 1.95 ± 0.66 | 3.12 ± 0.91 | 0.156 | Caspase 1, apoptosis-related cysteine peptidase | CASP1 | 2.68 ± 0.90 | 3.05 ± 1.42 | 0.741 | Glyceraldehyde-3-phosphate dehydrogenase | GAPDH | 2.14 ± 0.72 | 1.94 ± 0.57 | 0.771 | Intercellular adhesion molecule 1 | ICAM1 | 0.61 ± 0.22 | 0.62 ± 0.36 | 0.982 | Interleukin 1 receptor, type II | IL1R2 | 1.88 ± 0.53 | 1.24 ± 0.34 | 0.153 | Interleukin 2 receptor, gamma | IL2RG | 2.65 ± 1.37 | 2.20 ± 0.93 | 0.713 | Integrin, alpha M | ITGAM | 1.56 ± 0.48 | 1.25 ± 0.51 | 0.537 | Integrin, beta 2 | ITGB2 | 1.52 ± 0.35 | 1.54 ± 0.38 | 0.949 | Mitogen-activated protein kinase 1 | MAPK1 | 1.77 ± 0.83 | 1.20 ± 0.37 | 0.355 | Mitogen-activated protein kinase 3 | MAPK3 | 1.41 ± 0.36 | 0.90 ± 0.34 | 0.156 | Mitogen-activated protein kinase 14 | MAPK14 | 2.18 ± 0.60 | 1.51 ± 0.45 | 0.211 | Phosphodiesterase 4B, cAMP-specific | PDE4B | 1.44 ± 0.36 | 1.44 ± 0.55 | 0.999 | Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | PTGS2 | 2.43 ± 0.84 | 3.42 ± 1.13 | 0.338 | Tumor necrosis factor receptor superfamily, member 1A | TNFRSF1A | 1.47 ± 0.36 | 1.40 ± 0.33 | 0.841 | Tumor necrosis factor receptor superfamily, member 1B | TNFRSF1B | 1.72 ± 0.66 | 0.86 ± 0.36 | 0.099 |
|
|
Mean ± SEM. = 15–24. = 11–15.
|