Chemerin15-Ameliorated Cardiac Ischemia-Reperfusion Injury Is Associated with the Induction of Alternatively Activated Macrophages

Figure 1

Chemerin15 (C15) decreased the myocardial infarct size and improved the hemodynamic performance following ischemia/reperfusion (I/R). ((a) and (b)) Quantification of the area at risk/left ventricular area (AAR/LV) and infarct area/AAR (I/AAR) 24 h after reperfusion (). (c) Serum cardiac troponin T (cTnT) was measured in the sham, I/R, and I/R+C15 groups at 24 h after I/R (). (d) The ejection fraction (%EF) was measured 48 h after reperfusion (). < 0.05 versus the I/R or sham groups; < 0.05 versus the I/R group.

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