Metalloproteinases and Their Tissue Inhibitors in Comparison between Different Chronic Pneumopathies in the Horse

Table 6

MMP-2, MMP-9, TIMP-1, TIMP-2 ELISA, and MMP-8 fluorimetry measurements. The results are expressed as mean ± SD. shows significant increases to controls at , significant increase in IAD compared to RAO and CIP, and significant increase in RAO compared to IAD and CIP. RAO: recurrent airway obstruction, IAD: inflammatory airway disease, and CIP: chronic interstitial pneumopathy.

	MMP-2 [ng/mL]	MMP-9 [pg/mL]	MMP-8 [RFU]	TIMP-1 [pg/mL]	TIMP-2 [ng/mL]
Controls ()	2.49 ± 0.83	176.29 ± 60.22	3,556.63 ± 176	117.54 ± 45.62	18.06 ± 2.37
RAO ()	5.21 ± 0.77	433.34 ± 89.05	21,802.03 ± 21,047	328.19 ± 62.83	27.75 ± 5.08
IAD ()	7.67 ± 15.5	312.06 ± 23.92	5,366.17 ± 1,434	308.92 ± 8.24	25.42 ± 1.38
CIP ()	2.81 ± 0.34	263.2 ± 23.85	3,800.36 ± 403	205.47 ± 97.63	21.19 ± 2.45