Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2015, Article ID 587378, 11 pages
http://dx.doi.org/10.1155/2015/587378
Research Article

The Immediate Intramedullary Nailing Surgery Increased the Mitochondrial DNA Release That Aggravated Systemic Inflammatory Response and Lung Injury Induced by Elderly Hip Fracture

1Department of Orthopaedics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China
2Department of Orthopaedics, Beijing Army General Hospital, Beijing 100700, China
3Department of Respiratory Diseases, Chronic Airways Diseases Laboratory, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China

Received 12 December 2014; Revised 8 February 2015; Accepted 20 February 2015

Academic Editor: Chung-Hsi Hsing

Copyright © 2015 Li Gan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • Jing-Feng Chen, Shi-Ying Luo, and Liao Cui, “Effect of tanshinol on bone mineral density and microstructure of proximal tibias in rats with bone loss induced by glucocorticoid,” Chinese Pharmacological Bulletin, vol. 31, no. 12, pp. 1681–1687, 2015. View at Publisher · View at Google Scholar
  • W Jiang, M Li, F He, Z Bian, J Liu, Q He, X Wang, T Sun, and L Zhu, “Dopamine D1 receptor agonist A-68930 inhibits NLRP3 inflammasome activation and protects rats from spinal cord injury-induced acute lung injury,” Spinal Cord, 2016. View at Publisher · View at Google Scholar
  • Wu Jiang, Maoqiang Li, Fan He, Liulong Zhu, Wangxiang Yao, Zhenyu Bian, and Xuepeng Wang, “Protective Effects of Asiatic Acid Against Spinal Cord Injury-Induced Acute Lung Injury in Rats,” Inflammation, vol. 39, no. 6, pp. 1853–1861, 2016. View at Publisher · View at Google Scholar
  • Chaoyi Qin, Hong Qian, Ruiqi Liu, Fei Xu, Yajiao Li, Zhenghua Xiao, Qian He, Wei Meng, Jun Gu, and Jia Hu, “Potential mechanism of post-acute aortic dissection inflammatory responses: The role of mtDNA from activated platelets,” Cardiology (Switzerland), vol. 135, no. 4, pp. 228–235, 2016. View at Publisher · View at Google Scholar
  • Wujian Xu, and Yong Song, “Biomarkers for patients with trauma associated acute respiratory distress syndrome,” Military Medical Research, vol. 4, no. 1, 2017. View at Publisher · View at Google Scholar
  • Xiao-Dan Zhao, Wen-Li Zhang, Hao Liu, Tao Li, and Quan Gong, “Epigallocatechin gallate attenuates hip fracture-induced acute lung injury by limiting mitochondrial DNA (mtDNA) release,” Medical Science Monitor, vol. 23, pp. 3367–3372, 2017. View at Publisher · View at Google Scholar
  • Jian-zheng Zhang, Juan Wang, Wen-chun Qu, Xiao-wei Wang, Zhi Liu, Ji-xin Ren, Li Han, and Tian-sheng Sun, “Plasma mitochondrial DNA levels were independently associated with lung injury in elderly hip fracture patients,” Injury, vol. 48, no. 2, pp. 454–459, 2017. View at Publisher · View at Google Scholar
  • Xiaowei Wang, Jianzheng Zhang, Juan Wang, Zhi Liu, Jixin Ren, and Tiansheng Sun, “Early surgery increases mitochondrial DNA release and lung injury in a model of elderly hip fracture and chronic obstructive pulmonary disease,” Experimental and Therapeutic Medicine, vol. 14, no. 5, pp. 4541–4546, 2017. View at Publisher · View at Google Scholar
  • Shapkin, and Seliverstov, “Advantages and dangers of early osteosynthesis of femur in polytrauma with chest injury,” Sklifosovsky Journal Emergency Medical Care, vol. 6, no. 3, pp. 238–245, 2017. View at Publisher · View at Google Scholar
  • Andrew Bennett, Hsin Li, Aakash Patel, Kevin Kang, Piyush Gupta, Jack Choueka, and Dennis E. Feierman, “Retrospective Analysis of Geriatric Patients Undergoing Hip Fracture Surgery: Delaying Surgery Is Associated With Increased Morbidity, Mortality, and Length of Stay,” Geriatric Orthopaedic Surgery & Rehabilitation, vol. 9, pp. 215145931879526, 2018. View at Publisher · View at Google Scholar
  • Kabilan Thurairajah, Gabrielle Daisy Briggs, and Zsolt Janos Balogh, “The source of cell-free mitochondrial DNA in trauma and potential therapeutic strategies,” European Journal of Trauma and Emergency Surgery, 2018. View at Publisher · View at Google Scholar
  • Xiaobin Chen, Jianzheng Zhang, Zhi Liu, Simeng Zhang, and Tiansheng Sun, “Specific microRNA signatures responsible for immune disturbance related to hip fracture in aged rats,” Journal of Orthopaedic Surgery and Research, vol. 13, no. 1, 2018. View at Publisher · View at Google Scholar