Human Leucocyte Antigen-G (HLA-G) and Its Murine Functional Homolog Qa2 in the Trypanosoma cruzi Infection
Table 2
Odds Ratio and 95% Confidence Interval values obtained from the comparisons of genotype and allele frequencies of variation sites at HLA-G 3′ untranslated region (3′
UTR) between different presentation forms of Chagas disease and healthy controls.
Genotypes and alleles
Comparison
OR (95% CI)
Comparison
OR (95% CI)
Comparison
OR (95% CI)
+3003CT
W versus H
0.495 (0.29–0.86)
CDM versus H
0.459 (0.25–0.84)
D versus H
0.426 (0.19–0.97)
+3003TT
W versus H
2.089 (1.21–3.61)
CDM versus H
2.252 (1.23–4.11)
D versus H
2.428 (1.07–5.53)
+3003C
W versus H
0.506 (0.30–0.85)
CDM versus H
0.472 (0.27–0.83)
D versus H
0.440 (0.20–0.97)
+3003T
W versus H
1.977 (1.18–3.31)
CDM versus H
2.119 (1.20–3.74)
D versus H
2.272 (1.03–4.99)
+3010GC
W versus H
0.610 (0.39–0.95)
C versus H
0.414 (0.21–0.81)
+3027AC
D versus I
0.041 (0.002–0.75)
D versus M
0.036 (0.002–0.71)
C versus D
17.473 (0.96–318.00)
D versus H
0.073 (0.004–1.23)
+3027CC
D versus I
24.254 (1.33–443.84)
D versus M
27.439 (1.42–531.65)
C versus D
0.057 (0.003–1.04)
D versus H
14.785 (0.87–250.35)
+3027A
D versus I
0.045 (0.002–0.81)
D versus M
0.040 (0.002–0.75)
C versus D
16.431 (0.91–295.23)
D versus H
0.067 (0.004–1.13)
+3027C
D versus I
22.324 (1.24–402.08)
D versus M
25.180 (1.33–477.12)
C versus D
0.061 (0.003–1.09)
D versus H
14.847 (0.89–248.81)
+3035CC
D versus M
3.843 (1.14–12.99)
C versus D
0.291 (0.10–0.82)
D versus H
3.700 (1.49–9.20)
+3035CT
D versus M
0.260 (0.08–0.88)
D versus H
0.308 (0.12–0.77)
+3035C
D versus I
3.229 (1.14–9.13)
D versus M
3.358 (1.07–10.57)
C versus D
0.280 (0.11–0.74)
D versus H
3.603 (1.50–8.65)
+3035T
D versus I
0.310 (0.11–0.88)
D versus M
0.298 (0.09–0.94)
C versus D
3.576 (1.34–9.51)
D versus H
0.278 (0.12–0.67)
+3142GC
W versus H
0.616 (0.40–0.95)
C versus D
0.390 (0.18–0.86)
C versus H
0.391 (0.20–0.77)
+3142GG
D versus I
0.398 (0.16–0.96)
D versus M
0.327 (0.12–0.90)
C versus D
2.531 (1.10–5.80)
+3187GG
W versus H
2.902 (1.20–7.03)
CDM versus H
2.843 (1.13–7.14)
C versus H
3.442 (1.14–10.35)
+3196CC
CDM versus H
0.586 (0.37–0.93)
M versus H
0.401 (0.16–0.99)
+3196GC
CDM versus H
1.697 (1.06–2.71)
CDM versus I
2.284 (1.07–4.88)
I versus M
0.267 (0.09–0.78)
M versus H
2.787 (1.15–6.77)
I (indeterminate). C (cardiac). D (digestive). M (mixed). CDM (patients presenting clinically detected disease). W (whole group). H (healthy control). OR, Odds Ratio. 95% CI, 95% Confidence Interval.
