Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expression of Protumor Factors Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in a GM-CSF Receptor-Independent Manner in Cervical Cancer Cells
Table 2
Patient characteristics.
Characteristic
iNOS
COX-2
GM-CSF
Moderate/ strong ()
Negative/ weak ()
Moderate/ strong ()
Negative/ weak ()
Moderate/ strong ()
Negative/ weak ()
Age, years
46.26 ± 6.58
47.85 ± 7.66
0.304
47.18 ± 7.11
46.79 ± 7.21
0.800
47.93 ± 7.50
46.02 ± 6.62
0.213
Tumors size, cm
3.03 ± 1.21
2.86 ± 1.17
0.803
3.18 ± 1.16
2.80 ± 1.10
0.583
2.94 ± 1.01
3.02 ± 1.11
0.892
FIGO stage
Ib1
9
17
0.027
10
16
0.019
12
14
0.983
Ib2
8
13
9
12
10
11
IIa
15
9
16
8
12
12
IIb
14
2
14
2
10
6
HPV infection
HPV(+)
34
31
0.856
38
30
0.876
29
26
0.843
HPV(−)
12
10
11
8
15
17
LN metastasis
Yes
32
20
0.048
33
17
0.034
26
17
0.068
No
14
21
16
21
18
26
Data are presented as mean ± SD. The values were calculated with chi-square or Fisher’s exact tests.
