Association of Metabolic Syndrome with the Adiponectin to Homeostasis Model Assessment of Insulin Resistance Ratio
Table 1
General characteristics of the study participants according to presence or absence of MetS.
Parameters
Men ()
Women ()
Without MetS ()
With MetS ()
Without MetS ()
With MetS ()
Anthropometric characteristics
Age (y)
44.44 ± 13.98
50.34 ± 11.47
<0.01
40.17 ± 12.25
49.38 ± 11.48
<0.01
Waist circumference (cm)
83.07 ± 9.31
99.14 ± 8.17
<0.01
77.46 ± 9.67
91.52 ± 8.27
<0.01
BMI (kg/m2)
23.10 ± 3.09
28.60 ± 3.37
<0.01
22.60 ± 3.43
27.39 ± 3.65
<0.01
Systolic BP (mmHg)
126.80 ± 21.61
144.60 ± 20.34
<0.01
122.60 ± 19.89
144.73 ± 25.60
<0.01
Diastolic BP (mmHg)
81.59 ± 13.33
92.39 ± 12.12
<0.01
78.72 ± 12.26
92.03 ± 12.85
<0.01
Current smoker ( [%])
258 (51.29%)
214 (81.06%)
<0.01
231 (38.89%)
214 (80.15%)
<0.01
Metabolic characteristics
Total cholesterol (mmol/L)
4.14 ± 0.98
4.75 ± 1.23
<0.01
4.13 ± 1.08
4.57 ± 1.28
<0.01
TG (mmol/L)
1.01 ± 0.48
2.06 ± 1.30
<0.01
0.93 ± 0.42
1.55 ± 0.87
<0.01
HDL cholesterol (mmol/L)
1.42 ± 0.42
1.38 ± 0.57
<0.01
1.60 ± 0.43
1.31 ± 0.49
<0.01
LDL cholesterol (mmol/L)
2.19 ± 0.69
2.53 ± 0.97
<0.01
2.05 ± 0.69
2.49 ± 0.82
<0.01
FBG (mmol/L)
4.47 ± 0.93
5.57 ± 1.47
<0.01
4.28 ± 0.79
5.19 ± 1.22
<0.01
Insulin (μIU/dL)
10.80 (7.01–14.72)
14.95 (12.30–17.00)
<0.01
9.60 (7.20–15.50)
14.61 (8.40–17.50)
<0.01
HOMA-IR
2.05 (1.32–3.00)
3.31 (2.47–4.54)
<0.01
1.81 (1.37–3.08)
3.28 (1.77–4.31)
<0.01
Adiponectin (µg/mL)
5.78 (4.18–6.63)
4.04 (2.67–5.65)
<0.01
6.98 (5.43–8.40)
5.70 (3.93–8.12)
<0.05
A/H ratio
2.43 (1.50–3.95)
1.08 (0.75–1.91)
<0.01
3.30 (2.08–5.00)
2.02 (1.00–3.57)
<0.01
IL-6 (pg/mL)
0.65 (0.16–1.39)
1.58 (1.18–1.97)
<0.01
0.53 (0.15–1.33)
1.60 (0.99–2.01)
<0.01
Values are expressed as means ± SD or number (%), if not stated otherwise. Median values of adiponectin, fasting insulin, IL-6, and HOMA-IR are presented (lower quartile-upper quartile). SD, standard deviation; BMI, body mass index; TG, triglyceride; BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FBG, fasting blood glucose; HOMA-IR, homeostasis model assessment of insulin resistance; IL-6, interleukin-6; A/H ratio, adiponectin to homeostasis assessment-insulin resistance.
