Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line

Figure 1

Cells survival depends on the dose of aspirin. Cell survival of either untreated or aspirin treated (from 0.5 mM to 10 mM) Hek-293 cells for 24 hours. Trypan blue exclusion test analysis was used to analyze cell death (“trypan blue-not excluding”). “Trypan blue-not excluding” cell analysis is reported as percentage of dead cells, in aspirin treated compared to untreated cells. Data are reported as mean ± SD of 3 experiments performed.