Origin of Circulating Free DNA in Sepsis: Analysis of the CLP Mouse Model

Figure 4

Effect of neutrophil depletion on circulating free (cf) DNA. (a), (b) White blood cell number in (a) the blood and (b) ascites at 24 hours after the operation, with or without neutrophil depletion. (c), (d) Bacterial count of (c) the blood and (d) ascites cultures at 24 hours after the operation, with or without neutrophil depletion. (e) Amount of cf-DNA in the plasma at 24 hours after cecal ligation and puncture (CLP) or sham operation, with or without neutrophil depletion. Five mice from each group were used for each experiment.

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