Macrophage Migration Inhibitory Factor Interacting with Th17 Cells May Be Involved in the Pathogenesis of Autoimmune Damage in Hashimoto’s Thyroiditis

Table 1

Characteristics of patients with HT and healthy controls.

	HT	HT-A	HT-B	Healthy control	Normal; range
Cases ()	40	22	18	30	—
Gender (F/M)	35/5	19/3	16/2	26/4	—
Age (years)	28.93 ± 8.30	28.91 ± 9.21	28.94 ± 7.30	30.97 ± 6.39	—
TSH (mIU/L)	4.13 (1.82–6.25)^**	1.94 (0.99–3.06)	6.95 (5.12–16.18)^**	1.89 (1.15–2.59)	0.28–4.3
FT3 (pmol/L)	4.49 ± 1.32^*	4.97 ± 1.17	3.89 ± 1.27^**	5.23 ± 0.98	2.8–7.1
FT4 (pmol/L)	15.65 ± 3.04^*	16.58 ± 2.28	14.52 ± 3.50^**	17.29 ± 2.09	12–22
TPOAb (IU/mL)	200.00 (148.35–299.88)^**	171.00 (109.53–215.08)^**	294.75 (199.58–410.85)^**	14.25 (7.53–24.00)	0–34
TgAb (IU/mL)	489.75 (300.70–774.70)^**	335.15 (258.85–485.48)^**	717.55 (551.53–1055.58)^**	51.00 (19.75–84.25)	0–115
MUI (μg/L)	169.40	168.45	170.30	163.35	—

Data are shown as mean ± SD or median (25th–75th percentile) according to the distribution. HT-A, HT patient with normal thyroid function; HT-B, HT patient with subclinical or overt hypothyroidism; M, male; F, female; MUI, median of urine iodine. The P values represent different groups compared with healthy control (HC), , .