Research Article

Modulation of Extracellular ATP Content of Mast Cells and DRG Neurons by Irradiation: Studies on Underlying Mechanism of Low-Level-Laser Therapy

Figure 4

Response of MCs in rat tissue slices to 657 nm and 0.28 W/cm2 laser irradiation. (a) MCs in connective tissue slices isolated from rat skin. The left graph shows their smooth and complete plasma membrane. The right graph presents the same MCs stained by 0.5% TB. (b) MCs in tissue slices showed smooth cell membranes before irradiation (left graph). Some MCs started to degranulate once they were exposed to irradiation. The cell membrane became rough, and some black granules were seen scattered around the cell (right graph). The arrow points to degranulating cell. Irradiation times are given in the lower right corners.
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