Systemic Autoimmune, Rheumatic Diseases and Coinciding Psoriasis: Data from a Large Single-Centre Registry and Review of the Literature

Table 3

Patient characteristics with SLE associated with psoriasis.

The age of SLE onset	Comorbidity	Immunoserology	Actual clinical status	Therapy	Arthritis psoriatica	Corticosteroids (mg PED)	SLICC
27 yrs	Lupus nephritis, autoimmune thyroiditis	ANA, aSSA, aSSB, aTPO	Relapsing, remission by MMF	Cyclophosphamide, mycophenolate mofetil, methylprednisolone	Peripheral	25	1
54 yrs	Hypertension, gout, ischaemic heart disease, COPD, cataract	ANA, a-dsDNA	Relapsing	Chloroquine, azathioprine, methylprednisolone, etanercept	Axial	12.5	4
45 yrs	—	ANA, a-SM, a-SSA	Remission	Oral methotrexate, leflunomide, chloroquine	—	—	0
24 yrs	Raynaud’s syndrome, cutaneous vasculitis	ANA, a-dsDNA, a-SSA, aSSB, 2GPI IgG, hypocomplementaemia	Relapsing	Methylprednisolone, azathioprine, intravenous cyclophosphamide, IVIG, plasmapheresis,	—	30	1
33 yrs	Autoimmune thyroiditis, nephrotic syndrome	ANA, a-TPO, lupus anticoagulant, aCL IgM	Relapsing	Methylprednisolone, chloroquine, oral methotrexate,	—	10	1
57 yrs	Sjögren’s syndrome	ANA, a-SSA, a-SSB, a-dsDNA, hypocomplementaemia	Relapsing	Oral methotrexate, methylprednisolone, sulfasalazine, intravenous cyclophosphamide	—	20	1
58 yrs	Sjögren’s syndrome, urticaria vasculitis, ILD	ANA, a-dsDNA, a-chromatin, hypocomplementaemia	Worsening of ILD, psoriasis, immunoserology	Oral methotrexate, sulfasalazine, intravenous cyclophosphamide	Axial	30	1
29 yrs	Sjögren’s syndrome	ANA, a-dsDNA, a-SSA, a-SSB, anti-RNP, a-U1RNP, a-TG	Worsening of psychosis, thrombocytopenia	Methylprednisolone	—	12.5	1

SLE: systemic lupus erythematosus, COPD: chronic obstructive pulmonary disease, ILD: interstitial lung disease, ANA: anti-nuclear antibody, ACPA: anti-citrullinated peptide antibody, a-SSA: anti-Sjögren’s syndrome A antibody, a-SSB: anti-Sjögren’s syndrome B antibody, anti-RNP: anti-ribonucleoprotein antibody, a-dsDNA: anti-double stranded deoxyribonucleic acid antibody, 2GPI IgG: beta 2 glycoprotein I IgG, aCL IgM: anti-cardiolipin antibody immunoglobulin M, aU1RNP: anti-U1 ribonucleoprotein antibody, a-TG: anti-thyroglobulin antibody, a-TPO: anti-thyreoid peroxidase antibody, MMF: mycophenolate mofetil, PED: prednisolone equivalent dose, and SLICC: systemic lupus international collaborating clinics.